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Phenotypes Associated with This Genotype
Genotype
MGI:5563905
cn11
Allelic
Composition		 Smotm2Amc/Smotm2Amc
Isl1tm1(cre)Tmj/Isl1+
Genetic
Background		 involves: 129S/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Isl1tm1(cre)Tmj mutation (0 available); any Isl1 mutation (37 available)
Smotm2Amc mutation (1 available); any Smo mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
blood vessel atresia ( J:204743 )
• embryos show severe inflow tract defects with pulmonary vein atresia
abnormal heart right ventricle morphology ( J:204743 )
• embryos show severe inflow tract defects with pulmonary vein atresia
abnormal blood circulation ( J:204743 )
• embryos show persistence of aortopulmonary collateral circulation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory