Phenotypes Associated with This Genotype

Genotype
MGI:5568619

hm1

• Allelic Composition: Rubie^SWR-J/Rubie^SWR-J
• Genetic Background: C57BL/10J-Chr 14^SWR/J/NcaMmnc

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

hyperactivity ( J:209710 )

bidirectional circling ( J:209710 )

• 54% penetrance

hearing/vestibular/ear

abnormal inner ear development ( J:209710 )

• E14.5 embryos lack distal rims of the lateral pouches that will form the lateral semicircular canals

abnormal lateral semicircular canal morphology ( J:209710 )

• truncated or severely distorted in 6 of 12 mice examined

• anterior and posterior canals are normal