behavior/neurological
• begins at 16 weeks of age
|
hyperactivity
(
J:50173
)
• begins at 16 weeks of age
|
• begins at 16 weeks of age
|
• 8 of 24 mice show stereotypy beginning at 16 weeks of age, consisting of generalized hyperactive behavior, including unidirectional rotations, backflips, and excessive grooming
|
nervous system
• approximately 20% fewer small and medium neurons in the striata
• neuronal loss is also seen in the hippocampus, thalamus, cerebral cortex, and cerebellum
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
Huntington's disease | DOID:12858 |
OMIM:143100 |
J:50173 |