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Phenotypes Associated with This Genotype
Genotype
MGI:5582489
cx1
Allelic
Composition		 Tg(KRT5-Nfkbia*)3Rto/0
Tg(Krt5-Tnfr1)#Rsab/0
Tnfrsf1atm1Mak/Tnfrsf1atm1Mak
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(KRT5-Nfkbia*)3Rto mutation (0 available)
Tg(Krt5-Tnfr1)#Rsab mutation (0 available)
Tnfrsf1atm1Mak mutation (2 available); any Tnfrsf1a mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:208995 )
• in most mice within 10 days

integument
skin inflammation ( J:208995 )
• within the first 3 to 4 days after birth
epidermal hyperplasia ( J:208995 )
• within the first 3 to 4 days after birth

immune system
skin inflammation ( J:208995 )
• within the first 3 to 4 days after birth

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory