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Phenotypes Associated with This Genotype
Genotype
MGI:5582604
Allelic
Composition		 Il6tm1Kopf/Il6tm1Kopf
Tg(H2-K-IL6)2Srj/0
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il6tm1Kopf mutation (9 available); any Il6 mutation (38 available)
Tg(H2-K-IL6)2Srj mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:185153 )
N
• mice exhibit normal spleen and lymph node size, normal IgG levels and do not show hyperplastic germinal centers, extramedullary hematopoiesis, or plasmacytosis in lymphoid tissues at 4-5 months of age

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
NOT viral infectious disease DOID:934 J:185153

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory