Analysis Tools
hearing/vestibular/ear
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• mice exhibit normal vestibular function, middle ear morphology and stria vascularis
• mice exhibit normal auditory brainstem response (ABR) threshold at 4 weeks and normal age-related ABR threshold increase
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• progressive degeneration
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• at the basal turn
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• non-uniform height
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• disorganized and disoriented
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• outer hair cell like in appearance (U-shape, often splayed stereocilia and two rows of stereocilia bundles per cell)
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• at 14 weeks
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• at the basal level at 8 weeks that extends to the middle region with age
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• severe at 4 weeks, progressive
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nervous system
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• at the basal turn
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• non-uniform height
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• disorganized and disoriented
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• outer hair cell like in appearance (U-shape, often splayed stereocilia and two rows of stereocilia bundles per cell)
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• at 14 weeks
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• in some places
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| nonsyndromic deafness | DOID:0050563 | J:207337 | ||
