vision/eye
• attenuated retinal vessels by 2 months of age
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• at 3 weeks of age there is 20-30% photoreceptor loss with slow progressive loss thereafter
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• by 2 months of age homozygotes exhibit areas of depigmentation and attenuated retinal vessels
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• at 1 month of age there is a lower ERG a-wave but near normal b-wave, and by six months of age neither cone or rod ERG waveforms are detectable
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pigmentation
cardiovascular system
• attenuated retinal vessels by 2 months of age
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nervous system
• at 3 weeks of age there is 20-30% photoreceptor loss with slow progressive loss thereafter
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
retinitis pigmentosa 41 | DOID:0110376 |
OMIM:612095 |
J:215591 |