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Phenotypes Associated with This Genotype
Genotype
MGI:5614112
cn1
Allelic
Composition		 Rb1tm2Brn/Rb1tm2Brn
Tg(Cyp1a1-cre)1Dwi/0
Genetic
Background		 involves: 129 * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rb1tm2Brn mutation (3 available); any Rb1 mutation (111 available)
Tg(Cyp1a1-cre)1Dwi mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal enterocyte proliferation ( J:215358 )
• increased proliferation of columnar epithelial cells of the villi

digestive/alimentary system
abnormal enterocyte proliferation ( J:215358 )
• increased proliferation of columnar epithelial cells of the villi

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory