Phenotypes Associated with This Genotype

Genotype
MGI:5616119

• Allelic Composition: Bmp10^b2b2711Clo/Bmp10^b2b2711Clo
• Genetic Background: C57BL/6J-Bmp10^b2b2711Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant (E16.5) exhibits a hypoplastic thymus.

cardiovascular system

pulmonary artery hypoplasia ( J:175213 )

double outlet right ventricle ( J:175213 )

subarterial ventricular septal defect ( J:175213 )

renal/urinary system

polycystic kidney ( J:175213 )

• with tubule dilations

integument

petechiae ( J:175213 )

endocrine/exocrine glands

thymus hypoplasia ( J:175213 )

hematopoietic system

thymus hypoplasia ( J:175213 )

immune system

thymus hypoplasia ( J:175213 )

limbs/digits/tail

curly tail ( J:175213 )

growth/size/body

polycystic kidney ( J:175213 )

• with tubule dilations

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
tetralogy of Fallot		DOID:6419	OMIM:187500	J:175213