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Phenotypes Associated with This Genotype
Genotype
MGI:5620504
ht2
Allelic
Composition
Gnao1tm2.1Rneu/Gnao1+
Genetic
Background
129S-Gnao1tm2.1Rneu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gnao1tm2.1Rneu mutation (0 available); any Gnao1 mutation (29 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• Background Sensitivity: 100% of mice on the 129S1/SvImJ background survive more than 1 year compared to premature lethality on a C57BL/6J background

behavior/neurological
N
• Background Sensitivity: female mice show no difference in susceptibility to pentylenetetrazol (PTZ) kindling compared to faster sensitization on a C57BL/6J background


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory