Phenotypes Associated with This Genotype

Genotype
MGI:5621173

• Allelic Composition: Tg(SOD1*)D-14Dbo/0
• Genetic Background: involves: C3H/HeJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

paralysis ( J:218091 )

• mice exhibit incomplete penetrance of paralysis between 500 and 730 days of age

nervous system

abnormal spinal cord morphology ( J:218091 )

• the spinal cords show mutant protein immunoreactive fibrillar inclusions

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
amyotrophic lateral sclerosis type 1		DOID:0060193	OMIM:105400	J:218091