Phenotypes Associated with This Genotype

Genotype
MGI:5629954

• Allelic Composition: Bscl2^tm1.1Gliu/Bscl2^tm1.1Gliu; Tg(Fabp4-cre)1Rev/0
• Genetic Background: involves: 129 * 129S4/SvJaeSor

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

lipodystrophy ( J:211072 )

♂ • males develop progressive lipodystrophy

homeostasis/metabolism

increased circulating insulin level ( J:211072 )

♂ • increase in fed plasma insulin levels

increased circulating cholesterol level ( J:211072 )

♂

reproductive system

reproductive system phenotype ( J:211072 )

♂N • males exhibit normal mating behavior and sire offspring at normal frequencies, indicating normal fertility, show normal serum FSH, LH, testosterone and estradiol levels, and exhibit normal sperm

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
male infertility		DOID:12336		J:211072