Phenotypes Associated with This Genotype

Genotype
MGI:5645264

• Allelic Composition: Zfp366^b2b2834Clo/Zfp366^b2b2834Clo
• Genetic Background: C57BL/6J-Zfp366^b2b2834Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 2834-003-3 (E14.5) presents with parallel great arteries, which is diagnosed as an overriding aorta by episcopic confocal histopathology

cardiovascular system

overriding aortic valve ( J:175213 )

ventricular septal defect ( J:175213 )

craniofacial

micrognathia ( J:175213 )

short snout ( J:175213 )

skeleton

micrognathia ( J:175213 )

limbs/digits/tail

syndactyly ( J:175213 )

renal/urinary system

hydronephrosis ( J:175213 )

vision/eye

microphthalmia ( J:175213 )

growth/size/body

short snout ( J:175213 )

endocrine/exocrine glands

thymus hypoplasia ( J:175213 )

hematopoietic system

thymus hypoplasia ( J:175213 )

immune system

thymus hypoplasia ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
DiGeorge syndrome		DOID:11198	OMIM:188400	J:175213