Phenotypes Associated with This Genotype

Genotype
MGI:5648021

• Allelic Composition: Plxnd1^b2b3150Clo/Plxnd1^b2b3150Clo
• Genetic Background: C57BL/6J-Plxnd1^b2b3150Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 3150-003-2 (E15.5) exhibits a hypoplastic and malpositioned.

cardiovascular system

right aortic arch ( J:175213 )

vascular ring ( J:175213 )

abnormal left subclavian artery morphology ( J:175213 )

persistent truncus arteriosus ( J:175213 )

common atrium ( J:175213 )

atrioventricular septal defect ( J:175213 )

ventricular septal defect ( J:175213 )

endocrine/exocrine glands

thymus hypoplasia ( J:175213 )

hematopoietic system

thymus hypoplasia ( J:175213 )

digestive/alimentary system

cleft palate ( J:175213 )

growth/size/body

cleft palate ( J:175213 )

short snout ( J:175213 )

immune system

thymus hypoplasia ( J:175213 )

renal/urinary system

absent kidney ( J:175213 )

craniofacial

micrognathia ( J:175213 )

cleft palate ( J:175213 )

short snout ( J:175213 )

skeleton

micrognathia ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
DiGeorge syndrome		DOID:11198	OMIM:188400	J:175213