Phenotypes Associated with This Genotype

Genotype
MGI:5648857

• Allelic Composition: Prickle1^tm1Asw/Prickle1^tm1.2Asw
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

fused lower incisors ( J:213772 )

• fused mandibular incisors

prominent forehead ( J:213772 )

flattened snout ( J:213772 )

• flat nose

short snout ( J:213772 )

growth/size/body

fused lower incisors ( J:213772 )

• fused mandibular incisors

prominent forehead ( J:213772 )

flattened snout ( J:213772 )

• flat nose

short snout ( J:213772 )

decreased body length ( J:213772 )

limbs/digits/tail

brachydactyly ( J:213772 )

• shortened digital bones

kinked tail ( J:213772 )

skeleton

fused lower incisors ( J:213772 )

• fused mandibular incisors

decreased length of long bones ( J:213772 )

• shortened long bones and digital bones

abnormal vertebrae development ( J:213772 )

• incomplete and distorted vertebrae formation in the spinal cord

vision/eye

ocular hypertelorism ( J:213772 )

abnormal eyelid morphology ( J:213772 )

• abnormal appearance of eyelid and eyelashes

abnormal eyelid cilium morphology ( J:213772 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
autosomal recessive Robinow syndrome		DOID:0060764	OMIM:268310	J:213772