neoplasm
• tamoxifen treated mice develop oral tumors; tumors grow faster than in single conditional Kras mutants
• oral tumors of tamoxifen treated mice are papillomas that express HPV-biomarkers p16 and MCM7
• 14 days after tamoxifen treatment, mice treated with rapamycin for 3 days exhibit a transient decrease in tumor growth with regrowth after rapamycin is removed
• 14 days after tamoxifen treatment, mice that are treated with image-guided radiotherapy show regression of tumors
|
craniofacial
• tamoxifen treated mice develop oral tumors; tumors grow faster than in single conditional Kras mutants
• oral tumors of tamoxifen treated mice are papillomas that express HPV-biomarkers p16 and MCM7
• 14 days after tamoxifen treatment, mice treated with rapamycin for 3 days exhibit a transient decrease in tumor growth with regrowth after rapamycin is removed
• 14 days after tamoxifen treatment, mice that are treated with image-guided radiotherapy show regression of tumors
|
growth/size/body
• tamoxifen treated mice develop oral tumors; tumors grow faster than in single conditional Kras mutants
• oral tumors of tamoxifen treated mice are papillomas that express HPV-biomarkers p16 and MCM7
• 14 days after tamoxifen treatment, mice treated with rapamycin for 3 days exhibit a transient decrease in tumor growth with regrowth after rapamycin is removed
• 14 days after tamoxifen treatment, mice that are treated with image-guided radiotherapy show regression of tumors
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
oral cavity cancer | DOID:8618 | J:210533 |