Analysis Tools
mortality/aging
|
• 11.1% mice are viable at weaning, indicating partial lethality
|
craniofacial
|
• length of Meckel's cartilage is shorter
|
|
• skull length is shorter at P0 with an approximate 5% reduction
• skull of surviving adult mice is shorter in length
|
|
• mandible length is shorter in embryos, at P0 and 4 weeks of age
|
round face
(
J:214744
)
|
• some mice that survive to adulthood exhibit a round facial structure
|
cleft palate
(
J:214744
)
|
• embryos exhibit a mucous cleft palate with a separation between the palate and the nasal septum at E17.5
• ossified palatine bones with a gap are seen at P0
|
growth/size/body
round face
(
J:214744
)
|
• some mice that survive to adulthood exhibit a round facial structure
|
cleft palate
(
J:214744
)
|
• embryos exhibit a mucous cleft palate with a separation between the palate and the nasal septum at E17.5
• ossified palatine bones with a gap are seen at P0
|
digestive/alimentary system
cleft palate
(
J:214744
)
|
• embryos exhibit a mucous cleft palate with a separation between the palate and the nasal septum at E17.5
• ossified palatine bones with a gap are seen at P0
|
skeleton
|
• length of Meckel's cartilage is shorter
|
|
• skull length is shorter at P0 with an approximate 5% reduction
• skull of surviving adult mice is shorter in length
|
|
• mandible length is shorter in embryos, at P0 and 4 weeks of age
|
respiratory system
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| Miller-Dieker lissencephaly syndrome | DOID:0060469 |
OMIM:247200 |
J:214744 | |
