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Phenotypes Associated with This Genotype
Genotype
MGI:5661329
Allelic
Composition
Col1a1tm4(CAG-FGFR2_iIIIb*K660N)Kkw/Col1a1+
Genetic
Background
involves: 129S4/SvJae * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col1a1tm4(CAG-FGFR2_iIIIb*K660N)Kkw mutation (0 available); any Col1a1 mutation (163 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• 40% of mice develop lung tumors with an average latency of about 64 weeks after intranasal delivery of an adenovirus expressing cre recombinase

respiratory system
• 40% of mice develop lung tumors with an average latency of about 64 weeks after intranasal delivery of an adenovirus expressing cre recombinase

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
lung cancer DOID:1324 OMIM:211980
OMIM:608935
OMIM:612571
OMIM:612593
OMIM:614210
J:214230


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory