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Phenotypes Associated with This Genotype
Genotype
MGI:5661822
cx12
Allelic
Composition		 Celsr1Crsh/Celsr1+
ScribCrc/Scrib+
Vangl2Lp/Vangl2+
Genetic
Background		 C3H.Cg-Vangl2Lp ScribCrc Celsr1Crsh
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Celsr1Crsh mutation (2 available); any Celsr1 mutation (146 available)
ScribCrc mutation (3 available); any Scrib mutation (54 available)
Vangl2Lp mutation (2 available); any Vangl2 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
craniorachischisis ( J:216413 )
• 2 of 3 mutants exhibit craniorachischisis

limbs/digits/tail
abnormal tail morphology ( J:216413 )
• 1 of 3 mice exhibits hindbrain exencephaly and a tail defect

nervous system
craniorachischisis ( J:216413 )
• 2 of 3 mutants exhibit craniorachischisis
exencephaly ( J:216413 )
• 1 of 3 mice exhibits hindbrain exencephaly and a tail defect

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory