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Phenotypes Associated with This Genotype
Genotype
MGI:5751549
cn4
Allelic
Composition		 Tlr5tm1.1Gewr/Tlr5tm1.1Gewr
Tg(Itgax-cre,-EGFP)4097Ach/?
Genetic
Background		 involves: C57BL/6J * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Itgax-cre,-EGFP)4097Ach mutation (5 available)
Tlr5tm1.1Gewr mutation (1 available); any Tlr5 mutation (57 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
adipose tissue

digestive/alimentary system
abnormal gut flora balance ( J:229155 )
• delayed clearance of pathobiont bacteria
• decreased distance of fecal bacteria from intestinal epithelial cells

immune system
immune system phenotype ( J:229155 )
N
• mice do not exhibit spontaneous colitis, low grade inflammation or metabolic syndrome

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory