hematopoietic system
• primary microglial cells exhibit impaired production of cytokines in response to LPS
|
immune system
• primary microglial cells exhibit impaired production of cytokines in response to LPS
|
nervous system
• primary microglial cells exhibit impaired production of cytokines in response to LPS
|
• astrocyte cultures treated with LPS show abnormal morphology, remaining flat shaped rather than star shape in response to activation
|
• mice exhibit impaired astrogliosis in response to systemic stress induced by lipopolysaccharide (LPS)
• primary astrocytes exhibit impaired production of cytokines in response to LPS
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
leukoencephalopathy with vanishing white matter | DOID:0060868 |
OMIM:PS603896 |
J:192103 |