homeostasis/metabolism
• erythrocyte pyruvate kinase activity in heterozygous mutant mice is elevated up to 160% that of wild-type mice.
• liver pyruvate kinase activity is elevated in mice heterozygous for this mutation.
• pyruvate kinase activity in brain, heart, kidney, lung, muscle, and spleen of mutant mice is similar to that observed in these organs from wild-type mice.
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