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Phenotypes Associated with This Genotype
Genotype
MGI:5766068
Allelic
Composition
Morc1Tg(Tyr)1Az/Morc1Tg(Tyr)1Az
Genetic
Background
involves: C57BL/6N * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Morc1Tg(Tyr)1Az mutation (1 available); any Morc1 mutation (82 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• females show normal vertical and horizontal locomotor activity and unaltered anxiety-related behavior
• females exhibit a lower latency to float on day 1 of the forced swim test and an increase in immobility on day 1 and 2 of the forced swim test
• in the learned helplessness paradigm of depression, females show more failures to escape and a tendency of increased latency to escape

endocrine/exocrine glands

reproductive system

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
melancholic depression DOID:1595 OMIM:608516
J:227356


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory