Phenotypes Associated with This Genotype

Genotype
MGI:5766068

• Allelic Composition: Morc1^Tg(Tyr)1Az/Morc1^Tg(Tyr)1Az
• Genetic Background: involves: C57BL/6N * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:227356 )

♀N • females show normal vertical and horizontal locomotor activity and unaltered anxiety-related behavior

abnormal depression-related behavior ( J:227356 )

♀ • females exhibit a lower latency to float on day 1 of the forced swim test and an increase in immobility on day 1 and 2 of the forced swim test

♀ • in the learned helplessness paradigm of depression, females show more failures to escape and a tendency of increased latency to escape

endocrine/exocrine glands

small testis ( J:227356 )

♂

reproductive system

small testis ( J:227356 )

♂

male infertility ( J:227356 )

♂

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
melancholic depression		DOID:1595	OMIM:608516	J:227356