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Phenotypes Associated with This Genotype
Genotype
MGI:5771804
cn3
Allelic
Composition		 Smarcb1tm2Sho/Smarcb1tm2Sho
Trp53tm1Brn/Trp53+
Tg(GFAP-cre)#Gtm/0
Genetic
Background		 involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smarcb1tm2Sho mutation (1 available); any Smarcb1 mutation (23 available)
Tg(GFAP-cre)#Gtm mutation (0 available)
Trp53tm1Brn mutation (21 available); any Trp53 mutation (244 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal brain white matter morphology ( J:226786 )
• lesions in the white matter of the corpus callosum and cingulum

neoplasm
neoplasm ( J:226786 )
N
• no neoplastic growth is seen in the brain

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory