Phenotypes Associated with This Genotype

Genotype
MGI:5791914

• Allelic Composition: Tg(Neurod2-Smo*A1)199Jols/0
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased tumor-free survival time ( J:221990 )

• at 8 months of age, 50% of mice have to be sacrificed due to tumor burden

neoplasm

increased medulloblastoma incidence ( J:221990 )

• mice start developing medullobalstoma at around 4 months of age

• 38% medulloblastoma incidence

nervous system

increased medulloblastoma incidence ( J:221990 )

• mice start developing medullobalstoma at around 4 months of age

• 38% medulloblastoma incidence

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
medulloblastoma		DOID:0050902	OMIM:155255	J:221990