Phenotypes Associated with This Genotype

Genotype
MGI:5796171

cx3

• Allelic Composition: Tg(Bglap2-TAg)1Rkho/0; Tnfsf11^tm1Pngr/Tnfsf11^tm1Pngr
• Genetic Background: involves: 129P2/OlaHsd * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

decreased osteosarcoma incidence ( J:234128 )

• mice exhibit suppression of osteosarcoma development with only 2 of 35 mice showing tumors

limbs/digits/tail

abnormal femur morphology ( J:234128 )

• femurs from 42 week old mice show only benign parosteal growths without evidence of malignant cells

skeleton

abnormal femur morphology ( J:234128 )

• femurs from 42 week old mice show only benign parosteal growths without evidence of malignant cells

decreased osteosarcoma incidence ( J:234128 )

• mice exhibit suppression of osteosarcoma development with only 2 of 35 mice showing tumors