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Phenotypes Associated with This Genotype
Genotype
MGI:5796173
cn1
Allelic
Composition		 Tg(Bglap2-TAg)1Rkho/0
Tg(Col1a1-cre)1Kry/0
Tnfrsf11atm1.1Pngr/Tnfrsf11atm1.1Pngr
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Bglap2-TAg)1Rkho mutation (0 available)
Tg(Col1a1-cre)1Kry mutation (2 available)
Tnfrsf11atm1.1Pngr mutation (0 available); any Tnfrsf11a mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased osteosarcoma incidence ( J:234128 )
• tumor onset, survival, tumor burden, and lung metastasis is comparable to single Tg(Bglap2-TAg)1Rkho hemizygous mice

skeleton
increased osteosarcoma incidence ( J:234128 )
• tumor onset, survival, tumor burden, and lung metastasis is comparable to single Tg(Bglap2-TAg)1Rkho hemizygous mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory