Phenotypes Associated with This Genotype

Genotype
MGI:5804204

• Allelic Composition: Cyp4v3^{tm1(KOMP)Vlcg}/Cyp4v3^{tm1(KOMP)Vlcg}
• Genetic Background: B6(Cg)-Cyp4v3^{tm1(KOMP)Vlcg}
• Cell Lines: 10578B-B5

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal fatty acids level ( J:230232 )

• plasma levels of C18:0 fatty acids are lower while C18:2 and C18:3 levels are higher in 12 month old mice

vision/eye

abnormal retina morphology ( J:230232 )

• mice exhibit corneoretinal crystal accumulation beginning at 6 months with confluent crystalline deposits by 12 months of age

abnormal optic choroid morphology ( J:230232 )

• 12 month old eyes show focal accumulation of Oil Red O lipid droplets within the choroid layer

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Bietti crystalline corneoretinal dystrophy		DOID:0050664	OMIM:210370	J:230232