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Phenotypes Associated with This Genotype
Genotype
MGI:5805821
Allelic
Composition
Ptentm1Rps/Pten+
Genetic
Background
B6.129S1-Ptentm1Rps/Nci
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptentm1Rps mutation (1 available); any Pten mutation (88 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• males switch between behaviors less often than wild-type mice but spend the same amount of time performing active behaviors
• males are involved in less attacking, both delivered to and received from the intruder male which is reflected in decreased agonistic behavior indicating reduced aggression
• males preform more digging than wild-type mice
• males show less social investigation, particularly of the anogenital region and approach and/or attend to the intruder less than wild-type mice

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
autism spectrum disorder DOID:0060041 J:235927


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory