Phenotypes Associated with This Genotype

Genotype
MGI:5818292

• Allelic Composition: Gnas^tm4Lsw/Gnas⁺
• Genetic Background: involves: 129S6/SvEvTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal blood homeostasis ( J:233851 )

• mice with a maternally inherited allele exhibit higher levels of serum FGF23

renal/urinary system

abnormal kidney morphology ( J:233851 )

• mice with a maternally inherited allele exhibit higher renal Cyp24a1 mRNA but not Cyp27b1 mRNA

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
pseudohypoparathyroidism type 1A		DOID:0080053	OMIM:103580	J:233851