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Phenotypes Associated with This Genotype
Genotype
MGI:5897799
cx3
Allelic
Composition		 Fan1tm1.1Jrou/Fan1tm1.1Jrou
Fancd2Gt(OST57859)Lex/Fancd2Gt(OST57859)Lex
Genetic
Background		 involves: 129P2/OlaHsd * 129S5/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fan1tm1.1Jrou mutation (0 available); any Fan1 mutation (99 available)
Fancd2Gt(OST57859)Lex mutation (0 available); any Fancd2 mutation (82 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased physiological sensitivity to xenobiotic ( J:232403 )
• increase in sensitivity to mitomycin C compared to either single homozygote

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory