Phenotypes Associated with This Genotype

Genotype
MGI:5922030

• Allelic Composition: Aipl1^tvrm119/Aipl1^tvrm119
• Genetic Background: C57BL/6J-Aipl1^tvrm119/Pjn

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

retina photoreceptor degeneration ( J:243745 )

• rapid photoreceptor degeneration is not evident at 8 or 12 days of age, but by 1 month of age only one layer of photoreceptor nuclei remain

vision/eye

retina photoreceptor degeneration ( J:243745 )

• rapid photoreceptor degeneration is not evident at 8 or 12 days of age, but by 1 month of age only one layer of photoreceptor nuclei remain

abnormal electroretinogram waveform feature ( J:243745 )

• dark-adapted ERG response amplitudes are reduced at 18 days of age

abnormal visual evoked potential ( J:243745 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Leber congenital amaurosis 4		DOID:0110332	OMIM:604393	J:243745