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Phenotypes Associated with This Genotype
Genotype
MGI:6101473
Allelic
Composition		 Fxntm1.1Pand/Fxntm1Mkn
Genetic
Background		 B6.Cg-Fxntm1.1Pand Fxntm1Mkn/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fxntm1.1Pand mutation (2 available); any Fxn mutation (42 available)
Fxntm1Mkn mutation (14 available); any Fxn mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal mitochondrial biogenesis ( J:242978 )
• mice exhibit a mitochondrial biogenesis defect, with decreases in mitochondrial copy number in brain and skeletal muscle tissue

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
Friedreich ataxia DOID:12705 J:242978

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory