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Phenotypes Associated with This Genotype
Genotype
MGI:6105929
hm2
Allelic
Composition
Acot13tm1Deco/Acot13tm1Deco
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Acot13tm1Deco mutation (0 available); any Acot13 mutation (11 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• increased core body temperature early during the dark phase, but not in the light phase, when housed at 30C and more pronounced at 22C
• increased core body temperature at the dark phase in mice housed at 22C when food is removed at the beginning of the dark phase and when mice were subsequently refed during the light phase
• early during the dark phase, but not in the light phase, when housed at 30C and more pronounced at 22C
• at the dark phase in mice housed at 22C when food is removed at the beginning of the dark phase and when mice were subsequently refed during the light phase
• however, genotype and diurnal variations are lost
• increased core body temperature early during the dark phase, but not in the light phase, when housed at 30C and more pronounced at 22C
• however, genotype and diurnal variations are lostn at 4C
• over a 24 hr period, in the light phase and in the dark phase when housed at 22C or 4C
• in the dark phase only when mice are housed at 30C
• in the dark phase in mice housed at 30C or 22C
• in the light and dark phase at 4C
• in mice following food withdrawal and refeeding
• however, food withdrawal eliminates differences
• slightly at 4C, but not at 30C or 22C
• in mice following food withdrawal and refeeding
• however, food withdrawal eliminates differences

growth/size/body
• initially but not after 24 h at 4C

behavior/neurological
• during the light phase when mice were housed at 30C
• during the dark phase when mice were housed at 30C
• slight during the light phase and more so during the dark phase when mice are housed at 22C
• during the light and dark phase of cold-exposed mice
• over 24 h and during the dark phase at both 30C and 22C
• however, activity levels are not altered by food withdrawal

adipose tissue


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory