Phenotypes Associated with This Genotype

Genotype
MGI:6111404

• Allelic Composition: Tcte1^{tm1a(KOMP)Wtsi}/Tcte1^{tm1a(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Tcte1^{tm1a(KOMP)Wtsi}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:243766 , J:243766 )

♀N • female fertility (J:243766)

♂N • testis weight (J:243766)

♂N • sperm number (J:243766)

♂N • spermatogenesis (J:243766)

♂N • acrosome morphology (J:243766)

♂N • tubules full of spermatozoa in caput epididymis (J:243766)

♂N • tubules full of spermatozoa in cauda epididymis (J:243766)

♂N • sperm axoneme morphology (J:243766)

abnormal gametes ( J:243766 )

♂ • spermatozoa morphology

♂ • significantly lower ATP levels in spermatozoa

abnormal sperm flagellum morphology ( J:243766 )

♂ • limited flagellar beating range

♂ • unbalanced flagellar beating

asthenozoospermia ( J:243766 )

♂ • decreased forwardly motile spermatozoa using a Computer Assisted Sperm Analyzer (CASA)

male infertility ( J:243766 )

♂ • no pups born from mating homozygous males to wildtype or heterozygous females

cellular

abnormal gametes ( J:243766 )

♂ • spermatozoa morphology

♂ • significantly lower ATP levels in spermatozoa

abnormal sperm flagellum morphology ( J:243766 )

♂ • limited flagellar beating range

♂ • unbalanced flagellar beating

asthenozoospermia ( J:243766 )

♂ • decreased forwardly motile spermatozoa using a Computer Assisted Sperm Analyzer (CASA)

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
male infertility		DOID:12336		J:243766