Phenotypes Associated with This Genotype

Genotype
MGI:6149723

ht3

• Allelic Composition: Usp15^L749R/Usp15^tm1Pgrs
• Genetic Background: involves: 129S1/SvImJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased susceptibility to parasitic infection induced morbidity/mortality ( J:259382 )

• in an experimental cerebral malaria model, mice infected with Plasmodium berghei Anka strain (PbA) are resistant (95% survival) to fatal encephalitis unlike wild-type mice

immune system

decreased susceptibility to experimental autoimmune encephalomyelitis ( J:259382 )

• in an experimental cerebral malaria model, mice infected with Plasmodium berghei Anka strain (PbA) are resistant (95% survival) to fatal encephalitis unlike wild-type mice

decreased susceptibility to parasitic infection induced morbidity/mortality ( J:259382 )

• in an experimental cerebral malaria model, mice infected with Plasmodium berghei Anka strain (PbA) are resistant (95% survival) to fatal encephalitis unlike wild-type mice