Phenotypes for Neurod6 Plp1 MGI:6160754 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Plp1^{tm1c(EUCOMM)Wtsi}/Y Neurod6^tm1(cre)Kan/Neurod6⁺
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Neurod6^tm1(cre)Kan mutation (0 available); any Neurod6 mutation (18 available)
Plp1^{tm1c(EUCOMM)Wtsi} mutation (0 available); any Plp1 mutation (18 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:245100 )

N	• no APP+axonal spheroids, microgliosis, astrogliosis, or increase in T-lymphocytes are seen in the hippocampal fimbria at 26 weeks of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
NOT	hereditary spastic paraplegia 2	DOID:0110773	OMIM:312920	J:245100

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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