Phenotypes Associated with This Genotype

Genotype
MGI:6164126

ht2

• Allelic Composition: Tafa3^em1Hssh/Tafa3⁺
• Genetic Background: C57BL/6NTac-Tafa3^em1Hssh

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased anxiety-related response ( J:257371 )

♂ • in the elevated plus maze test, male (but not female) heterozygotes spend significantly less time in the open arms than wild-type controls, indicating increased anxiety-like behavior

increased grooming behavior ( J:257371 )

♂ • male (but not female) heterozygotes spend a significantly longer time self-grooming than wild-type controls

increased locomotor activity ( J:257371 )

♀ • in the open field assay, female (but not male) heterozygotes show slightly increased locomotor activity limited to the 10-15 min period of the 30 min test relative to wild-type and homozygous mutant females

increased stereotypic behavior ( J:257371 )

♂ • in the marble burying test, male (but not female) heterozygotes bury significantly more marbles than wild-type controls, indicating increased repetitive (burying) behavior