Phenotypes Associated with This Genotype

Genotype
MGI:6196323

• Allelic Composition: Ret^tm2.1Cos/?; Tg(Th-MYCN)41Waw/0
• Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:261033 )

• mice begin to die around 100 days of age, with 50% survival at 250 days of age

neoplasm

increased neuroblastoma incidence ( J:261033 )

• mice develop stroma-poor neuroblastoma, with the majority of tumors showing signs of differentiation

nervous system

increased neuroblastoma incidence ( J:261033 )

• mice develop stroma-poor neuroblastoma, with the majority of tumors showing signs of differentiation

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
neuroblastoma		DOID:769		J:261033