Phenotypes Associated with This Genotype

Genotype
MGI:6257025

• Allelic Composition: Tg(APPV717F)109Ili/0
• Genetic Background: B6.Cg-Tg(APPV717F)109Ili

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:244104 )

• mice exhibit higher early mortality than wild-type mice, starting at 2 months of age

nervous system

amyloid beta deposits ( J:244104 )

• mice exhibit extracellular amyloid deposition starting at 6-9 months of age

homeostasis/metabolism

amyloid beta deposits ( J:244104 )

• mice exhibit extracellular amyloid deposition starting at 6-9 months of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Alzheimer's disease		DOID:10652		J:244104