Phenotypes Associated with This Genotype

Genotype
MGI:6259997

cx5

• Allelic Composition: Rps20^Mhdadsk4/Rps20⁺; Tg(Dct-lacZ)A12Jkn/0
• Genetic Background: involves: C3HeB/FeJ * C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

abnormal epidermal melanocyte morphology ( J:139244 )

• an increased number of Xgal+ cells (melanocytes) are first detected in the basal layer of the footpad epidermis at P3 and persist in the adult footpad, indicating postnatal epidermal melanocytosis

increased melanocyte number ( J:139244 )

• an increased number of Xgal+ cells (melanocytes) are first detected in the basal layer of the footpad epidermis at P3 and persist in the adult footpad

integument

abnormal epidermal melanocyte morphology ( J:139244 )

• an increased number of Xgal+ cells (melanocytes) are first detected in the basal layer of the footpad epidermis at P3 and persist in the adult footpad, indicating postnatal epidermal melanocytosis

embryo

abnormal melanoblast morphology ( J:139244 )

• a decreased number of Xgal+ cells (melanoblasts) is observed at E15.5 and other embryonic time points

• a ventral surface area devoid of Xgal+ cells is observed at E15.5

nervous system

abnormal melanoblast morphology ( J:139244 )

• a decreased number of Xgal+ cells (melanoblasts) is observed at E15.5 and other embryonic time points

• a ventral surface area devoid of Xgal+ cells is observed at E15.5