Phenotypes Associated with This Genotype

Genotype
MGI:6260006

cn7

• Allelic Composition: Rps6^tm1Gtho/Rps6⁺; Tg(Mitf-cre)7114Gsb/0
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

abnormal dermal pigmentation ( J:139244 )

• mice exhibit slightly decreased dermal pigmentation relative to control mice

abnormal epidermal pigmentation ( J:139244 )

• mice exhibit decreased epidermal pigmentation relative to control mice

reduced foot pad pigmentation ( J:139244 )

decreased tail pigmentation ( J:139244 )

decreased skin pigmentation ( J:139244 )

• mice exhibit lighter skin than control mice; both the epidermis and, to a lesser extent, the dermis are affected

integument

abnormal dermal pigmentation ( J:139244 )

• mice exhibit slightly decreased dermal pigmentation relative to control mice

abnormal epidermal pigmentation ( J:139244 )

• mice exhibit decreased epidermal pigmentation relative to control mice

reduced foot pad pigmentation ( J:139244 )

decreased tail pigmentation ( J:139244 )

decreased skin pigmentation ( J:139244 )

• mice exhibit lighter skin than control mice; both the epidermis and, to a lesser extent, the dermis are affected

limbs/digits/tail

reduced foot pad pigmentation ( J:139244 )

decreased tail pigmentation ( J:139244 )