Phenotypes Associated with This Genotype

Genotype
MGI:6272341

cn1

• Allelic Composition: Ctnnb1^tm2Kem/Ctnnb1^tm2Kem; Tg(Tyr-cre)1Lru/0
• Genetic Background: B6.Cg-Ctnnb1^tm2Kem Tg(Tyr-cre)1Lru

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

abnormal hair follicle melanogenesis ( J:176245 )

• at 7 days of age, mice show absence of pigmentation in the hair follicle bulbs, unlike wild-type controls

reduced hair shaft melanin granule number ( J:176245 )

• spectrophotometry revealed absence of melanin in hairs, unlike in wild-type controls

abnormal pinna hair pigmentation ( J:176245 )

• mice exhibit white ears, similar to their coat pigmentation

abnormal tail hair pigmentation ( J:176245 )

• mice exhibit white tails, similar to their coat pigmentation

absent coat pigmentation ( J:176245 )

• mice exhibit a white coat color, unlike the black coat color of wild-type controls

integument

abnormal hair follicle melanogenesis ( J:176245 )

• at 7 days of age, mice show absence of pigmentation in the hair follicle bulbs, unlike wild-type controls

reduced hair shaft melanin granule number ( J:176245 )

• spectrophotometry revealed absence of melanin in hairs, unlike in wild-type controls

abnormal pinna hair pigmentation ( J:176245 )

• mice exhibit white ears, similar to their coat pigmentation

abnormal tail hair pigmentation ( J:176245 )

• mice exhibit white tails, similar to their coat pigmentation

absent coat pigmentation ( J:176245 )

• mice exhibit a white coat color, unlike the black coat color of wild-type controls