Analysis Tools
renal/urinary system
kidney cyst
(
J:128557
)
|
• 17 month old mice show kidney cysts, however to a lesser extent than in homozygous mice
• however, lungs. liver, and spleen are normal
|
respiratory system
|
• mice exhibit mild emphysema, with 27% of mice spontaneously developing emphysema
• mice exhibit increased susceptibility to cigarette smoke-induced emphysema, with 100% of mice exhibiting airspace enlargement compared to 67% of wild-type mice and mutants showing more severe disease than controls
|
growth/size/body
kidney cyst
(
J:128557
)
|
• 17 month old mice show kidney cysts, however to a lesser extent than in homozygous mice
• however, lungs. liver, and spleen are normal
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| pulmonary emphysema | DOID:9675 |
OMIM:130700 |
J:270215 | |
