Phenotypes Associated with This Genotype

Genotype
MGI:6287156

• Allelic Composition: Mitf^{Tg(Tff3-Tmem207)2Tamo}/Mitf^{Tg(Tff3-Tmem207)2Tamo}
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

polycystic kidney ( J:244533 )

• multiple cysts in the cortex and medulla and in the corticomedullary junction

endocrine/exocrine glands

pancreas cyst ( J:244533 )

• some mice with renal cysts also have pancreatic cysts

homeostasis/metabolism

increased circulating creatinine level ( J:244533 )

• serum creatinine is increased in 8- and 16-week old mice, with a further increase at 1 year of age

liver/biliary system

liver cyst ( J:244533 )

• some mice with renal cysts also have small liver cysts

growth/size/body

pancreas cyst ( J:244533 )

• some mice with renal cysts also have pancreatic cysts

polycystic kidney ( J:244533 )

• multiple cysts in the cortex and medulla and in the corticomedullary junction

liver cyst ( J:244533 )

• some mice with renal cysts also have small liver cysts

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
polycystic kidney disease		DOID:0080322	OMIM:PS173900	J:244533