endocrine/exocrine glands
• variable size at 4 to 5 weeks of age
• however, size at 2 to 3 weeks is normal
|
• beginning at 4 weeks of age
• replaced with adipose in late chronic pancreatitis
|
• somewhat in late chronic pancreatitis
|
• in some mice at 4 to 5 weeks of age due to edema
|
• at 2 months of age
|
• in half of mice at 4 to 5 weeks of age
• in most mice at 2, 6 and 12 months of age
|
• in late chronic pancreatitis
|
• starting at 3 weeks and more frequently at 4 to 5 weeks of age with edema, infiltration of neutrophil granulocytes and macrophages, and widespread evidence of regeneration
|
• starting at 2 months and continuing through 6 and 12 months with adipose replacement proceeding to late chronic pancreatitis
|
homeostasis/metabolism
N |
• mice exhibit normal blood glucose at 12 months of age
|
• at 4 to 5 weeks of age
|
digestive/alimentary system
• beginning at 4 weeks of age
• replaced with adipose in late chronic pancreatitis
|
immune system
• starting at 3 weeks and more frequently at 4 to 5 weeks of age with edema, infiltration of neutrophil granulocytes and macrophages, and widespread evidence of regeneration
|
• starting at 2 months and continuing through 6 and 12 months with adipose replacement proceeding to late chronic pancreatitis
|
growth/size/body
• in some mice at 4 to 5 weeks of age due to edema
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
pancreatitis | DOID:4989 |
OMIM:167800 |
J:267764 |