Phenotypes Associated with This Genotype

Genotype
MGI:6317191

tg1

• Allelic Composition: Tg(Prnp-MAPT*)2652Gds/Tg(Prnp-MAPT*)2652Gds
• Genetic Background: B6.Cg-Tg(Prnp-MAPT*)2652Gds

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:244052 )

growth/size/body

decreased body weight ( J:244052 )

behavior/neurological

abnormal locomotor behavior ( J:244052 )

• mice exhibit exaggerated motor abnormalities compared to hemizygous mice

seizures ( J:244052 )

nervous system

seizures ( J:244052 )

reproductive system

reduced fertility ( J:244052 )