Phenotypes Associated with This Genotype

Genotype
MGI:6358746

hm1

• Allelic Composition: Sun5^em1Wli/Sun5^em1Wli
• Genetic Background: involves: C57BL/6J * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:247612 )

♂N • normal testes weight

teratozoospermia ( J:247612 )

♂ • significantly reduced percentage of motile spermatozoa in caudal epididymis

♂ • most of motile spermatozoa in caudal epididymis belong to slow- or medium-moving classes

♂ • normal sperm concentration in caudal epididymis

abnormal sperm axoneme morphology ( J:247612 )

♂

abnormal sperm connecting piece morphology ( J:247612 )

♂

abnormal sperm head morphology ( J:247612 )

♂ • majority of heads are round

♂ • the few normal shaped heads are separated from flagella

globozoospermia ( J:247612 )

♂ • majority of heads are round and are devoid of chromatin

absent sperm head ( J:247612 )

♂ • very low ratio of sperm with head versus tails only in caput, corpus and cauda epididymis

abnormal spermiation ( J:247612 )

♂ • spermatids misoriented (heads towards lumen) in stage VII-VIII seminiferous tubules

male infertility ( J:247612 )

♂

cellular

teratozoospermia ( J:247612 )

♂ • significantly reduced percentage of motile spermatozoa in caudal epididymis

♂ • most of motile spermatozoa in caudal epididymis belong to slow- or medium-moving classes

♂ • normal sperm concentration in caudal epididymis

abnormal sperm axoneme morphology ( J:247612 )

♂

abnormal sperm connecting piece morphology ( J:247612 )

♂

abnormal sperm head morphology ( J:247612 )

♂ • majority of heads are round

♂ • the few normal shaped heads are separated from flagella

globozoospermia ( J:247612 )

♂ • majority of heads are round and are devoid of chromatin

absent sperm head ( J:247612 )

♂ • very low ratio of sperm with head versus tails only in caput, corpus and cauda epididymis

mortality/aging

mortality/aging ( J:247612 )

N • viable