Phenotypes Associated with This Genotype

Genotype
MGI:6359828

• Allelic Composition: Ush1c^dfcr-4J/Ush1c^dfcr-4J
• Genetic Background: 129P3/J-Ush1c^dfcr-4J/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired swimming ( J:278662 )

• homozygotes fail to swim at the surface of water but instead roll underwater

head tossing ( J:278662 )

circling ( J:278662 )

• all homozygotes

hearing/vestibular/ear

increased or absent threshold for auditory brainstem response ( J:278662 )

deafness ( J:278662 )

• completely deaf when assessed by ABR at 1 month of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
autosomal recessive nonsyndromic deafness 18A		DOID:0110473	OMIM:602092	J:278662
Usher syndrome type 1C		DOID:0110830	OMIM:276904	J:278662