liver/biliary system
• mice develop hepatocellular carcinoma by 10 weeks of age
• mice kept on doxycycline until 8 weeks of age and then transferred to normal chow develop liver tumors
• 3 week old mice mice supplied with a nicotinamide riboside diet show prevention of liver tumors at 30 weeks of age
• 12 week old mice with tumors supplied with a nicotinamide riboside diet for 48 weeks show tumor regression
|
neoplasm
• mice develop hepatocellular carcinoma by 10 weeks of age
• mice kept on doxycycline until 8 weeks of age and then transferred to normal chow develop liver tumors
• 3 week old mice mice supplied with a nicotinamide riboside diet show prevention of liver tumors at 30 weeks of age
• 12 week old mice with tumors supplied with a nicotinamide riboside diet for 48 weeks show tumor regression
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
hepatocellular carcinoma | DOID:684 |
OMIM:114550 |
J:217463 |